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Product Overview

未标题-4.jpgGentleFectTM is a non-viral, non-liposomal peptide-based delivery platform designed forthe efficient transfection of primary cells and a broad spectrum of nucleic acid cargos, including plasmid DNA, mRNA, siRNA, and circRNA. By integrating a benign peptide architecture with controlled self-assembly, the system achieves high transfection efficiency while preserving cellular viability, providing a critical balance for gene-editing workflows and cell-therapy manufacturing. Engineered for GMP-compatible processes, GentleFectTM delivers a scalable and reproducible solution that meets the stringent demands of industrial-scale bioproduction.

Product Features

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    High efficiency
    Efficiently transfect various primary cells, including primary T cells, stem cells, etc.
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    Safety & Reliable
    Endogenous short-sequence peptide delivery, devoid of biological activity and non-toxic.
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    Lentiviral Alternative
    Bypassing lentiviral vectors removes safety risks and lowers production costs.
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    Industrial Customization
    GMP-like solutions for scalable pharmaceutical and cell therapy production, enabling seamless lab-to-clinic translation.

Core Application

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    Gene Editing
    A non-viral, high-efficiency gene-editing tool that replaces lentivirus and minimizes cellular damage.
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    Cell Therapy
    Lentivirus-free, high-efficiency delivery that shorten cycles,lowers costs, and scales under GMP control.

Non-Viral High-Efficiency Stem Cell Drug Development

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Non-Viral High-Efficiency T Cell Drug Development

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REFERENCE

[ 1 ]. Sun, Y, Wu, X, Li, J. et al. Phase-separating peptide coacervates with programmable material properties for universal intracellular delivery of macromolecules. Nat Commun 15, 10094 (2024).

[ 2 ]. Sun, Y, Lau, S.Y, Lim, Z.W. et al. Phase-separating peptides for direct cytosolic delivery and redox-activated release of macromolecular therapeutics. Nat. Chem. 14,274-283 (2022).